Maternal-related factors influencing retention of HIV-exposed infants in the early infant diagnosis (EID) care clinic at Nebbi General Hospital. A cross-sectional study.
DOI:
https://doi.org/10.51168/xx3amg10Keywords:
Maternal-related factors, retention of HIV-exposed, HIV testing, HIV statusAbstract
Background:
The study aimed to identify maternal-related characteristics influencing the retention of HIV-exposed infants in the EID Care Clinic of Nebbi General Hospital.
Methodology:
A descriptive cross-sectional study using quantitative methods was conducted at Nebbi General Hospital’s EID clinic to assess factors influencing retention of HIV-exposed infants (HEIs). The study targeted 44 caregivers of HEIs, selected through convenience sampling. Data were collected via a semi-structured questionnaire on socio-demographic and maternal-related factors, after obtaining informed consent. Completed questionnaires were checked, stored securely, and analyzed using Excel for descriptive statistics. Validity and reliability were ensured through supervisor review and pre-testing. Ethical approval was obtained, maintaining confidentiality, anonymity, and voluntary participation throughout the study.
Results:
Most respondents were aged 20-29 years (17; 38.6%) and 30-39 years (15; 34.1%), while only 5 (11.3%) were 40 years or older. Over half had secondary education (26; 59.1%), 10 (22.7%) had tertiary, and 8 (18.2%) had primary education. Regarding maternal-related factors, 28 (63.6%) were aware of the importance of HIV testing for their babies. Fear of stigma (23; 52.2%) was the main reason for missed appointments. Most mothers (24; 54.5%) had not disclosed their HIV status, 25 (56.8%) sometimes adhered to medication, and 27 (61.4%) often felt too sad or worried to attend follow-ups, affecting retention of HIV-exposed infants in the EID clinic.
Conclusion:
Maternal issues such as fear of stigma, non-disclosure of HIV status, emotional distress, and irregular ART adherence greatly reduced clinic attendance.
Recommendation:
The Ministry of Health should strengthen maternal counseling programs to improve mothers’ knowledge of HIV and Early Infant Diagnosis.
References
1. Akunzirwe, R., Harris, J. R., Kawungezi, P. C., Wanyana, M. W., Lutalo, T., Namukanja, P. M., Delaney, A., Migisha, R., Nyamugisa, E., & Ondo, D. (2025). Complete testing coverage for the early infant diagnosis algorithm and associated factors among infants exposed to HIV, Uganda, 2017-2019. PLoS One, 20(6), e0324338. https://doi.org/10.1371/journal.pone.0324338
2. Alshehri, M. H., Alqahtani, M. A., Alshehri, S. M., Alturki, R. I., Alshiha, K. A., Alqahtani, M. A., & Alshehri, S. M. (2021). Knowledge and attitude of basic life support among medical students at Al-Imam Muhammad Ibn Saud Islamic University in Riyadh, Saudi Arabia. Middle East Journal of Family Medicine, 7(10).
3. Ankunda, R., Cumber, S. N., Atuhaire, C., Kabanda, T., Nkfusai, C. N., Wirsiy, F. S., & Turyakira, E. (2020). Loss to follow-up and associated maternal factors among HIV-exposed infants at the Mbarara Regional Referral Hospital, Uganda: A retrospective study. BMC Infectious Diseases, 20(1), 235.
https://doi.org/10.1186/s12879-020-04964-1
4. Apangu, P., Izudi, J., Bajunirwe, F., Mulogo, E., & Batwala, V. (2019). Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: A retrospective cohort study. BMC Public Health, 19(1), 436.
https://doi.org/10.1186/s12889-019-6754-9
5. Chapuma, C. I. J., Sakala, D., Nyang'Wa, M. N., Hosseinipour, M. C., Mbeye, N., Matoga, M., Kumwenda, M. K., Chikweza, A., Nyondo‐Mipando, A. L., & Mwapasa, V. (2024). Examining barriers to antiretroviral therapy initiation in infants living with HIV in sub‐Saharan Africa despite the availability of point‐of‐care diagnostic testing: A narrative systematic review. Journal of the International AIDS Society, 27, e26284.
https://doi.org/10.1002/jia2.26284
6. Gaitho, D., Kinoti, F., Mwaniki, L., Kemunto, D., Ogoti, V., Njigua, C., Kubo, E., Langat, A., & Mecha, J. (2021). Factors associated with the timely uptake of initial HIV virologic test among HIV-exposed infants attending clinics within a faith-based HIV program in Kenya: A cross-sectional study. BMC Public Health, 21(1), 569. https://doi.org/10.1186/s12889-021-10587-1
7. Hoosen, N. (2021). Interventions for improving adherence and retention in HIV-infected women on ART during antenatal and postnatal care: A systematic review.
8. Hunt, J. H., Peay, H. L., & Henderson, G. E. (2024). Facilitators and barriers to adherence to anti-retroviral treatment among pregnant or breastfeeding women living with HIV and perinatally infected infants: A scoping review. AIDS and Behavior, 28(9), 2910-2925. https://doi.org/10.1007/s10461-024-04373-4
9. Kamble, S., Gawde, N., Goel, N., Thorwat, M., Nikhare, K., Bembalkar, S., Kamble, S., Brahme, R., Pawar, S., & Sahoo, R. (2023). Access, timeliness, and retention for HIV testing under the early infant diagnosis (EID) program, India. Scientific Reports, 13(1), 5638. https://doi.org/10.1038/s41598-023-32056-y
10. Nikhare, K., Gawde, N., Kamble, S., Goel, N., Kamble, S., Pawar, S., More, P., Kapoor, N., Verma, V., & Kushwaha, B. S. (2024). Caregivers' experiences of accessing HIV early infant diagnosis (EID) services and their barriers and facilitators, India. BMC Health Services Research, 24(1), 24. https://doi.org/10.1186/s12913-023-10500-z
11. Yeboa, N. K., Muwanguzi, P., Olwit, C., Osingada, C. P., & Ngabirano, T. D. (2023). Prevalence and associated factors of postpartum depression among mothers living with HIV at an urban postnatal clinic in Uganda. Women's Health, 19, 17455057231158472. https://doi.org/10.1177/17455057231158471
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Copyright (c) 2026 Judith Peace Acom, Hasifa Nansereko, Immaculate Prosperia Naggulu, Jane Frank Nalubega (Author)
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